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Editor Profiles

Khue vu nguyen , Professor, Editor Profiles

PUBLICATIONS 1. K.V. NGUYEN and J.C. GALIN Anti-inflammatory polymer-bound steroids for topical applications I: Synthesis and characterization. Journal of Applied Polymer Science, 30, 2761-2778 (1985). 2. K.V. NGUYEN and L. JUNG Study of the retention of child-dose drugs on cellulose ester membranes during in-line intravenous filtration. Sciences Techniques et Pratiques Pharmaceutiques, 1, 201-207 (1985). 3. K.V. NGUYEN, L. JUNG, G. COUPIN and P. POINDRON Anti-inflammatory polymer-bound steroids for topical applications II: Controlled release of the steroids. Journal of Polymer Science: Polymer Chemistry Edition, 24, 359-373 (1986). 4. B. RIHN, F. BISSERET, R. GIRARDOT, J.M. SCHEFTEL, K.V. NGUYEN and H. MONTEIL Fast protein purification of Clostridium difficile cytotoxin. Journal of Chromatography, 428, 408-414 (1988). 5. K.V. NGUYEN, C. HECKEL, F. BISSERET, B. RIBIN, R. GIRARDOT and H. MONTEIL Enzyme-linked immunosorbent assay for detection of Clostridium difficile toxine B. Archives of Toxicology, Suppl. 12, 453-456 (1988). 6. F. BISSERET, G. KEITH, B. RIHN, I. AMIRI, B. WERNEBURG, R. GIRARDOT, O. BALDACINI, G. GREEN, K.V. NGUYEN and H. MONTEIL Clostridium difficile toxin B: Characterization and sequence of three peptides. Journal of Chromatography, 490, 91-100 (1989). Curriculum Vitae Khue Nguyen 14 7. K.V. NGUYEN, B. RIHN, C. HECKEL, F. BISSERET, R. GIRARDOT and H. MONTEIL Enzyme immunoassay (ELISA) for detection of Clostridium difficile toxin B in specimens of faeces. Journal of Medical Microbiology, 31, 251-257 (1990). 8. K.V. NGUYEN, C.M. WOLFF, J.L. SERIS and J.P. SCHWING Study on a complete lyophilizate for rapid colorimetric enzymatic creatinine assay. Analusis, 18, 582-587 (1990). 9. K.V. NGUYEN, C.M. WOLFF, J.L. SERIS and J.P. SCHWING Immobilized enzyme electrode for creatinine determination in serum. Analytical Chemistry, 63, 611-614 (1991). 10. K.V. NGUYEN and R.F. MAES Evaluation of an enzyme-linked immunosorbent assay for detection of antibodies to bovine leukemia virus in serum and milk. Journal of Clinical Microbiology, 31, 979-981 (1993). 11. K.V. NGUYEN, L.E. SABATIER, M. GOELDNER, C. BOUDIER, G. JAMET, J.M. WARTER and P. POINDRON Stabilization of dry immobilized acetylcholinesterase on microtitration plates for colorimetric determination of its inhibitors in water and biological fluids. Enzyme and Microbial Technology, 20, 18-23 (1997). 12. K.V. NGUYEN, C.M. WOLFF, J.M. WARTER and P. POINDRON Stabilization of dry immobilized acetylcholinesterase on nitrocellulose membrane for rapid colorimetric screening of its inhibitors in water and biological fluids. Analytical Letters, 31, 2457-2473 (1998). Curriculum Vitae Khue Nguyen 15 13. K.V. NGUYEN, N. LECLERC, C.M. WOLFF, P. KENNEL, P. FONTENEAU, R. DEYES, J.M. WARTER and P. POINDRON Protection of immunoreactivity of dry immobilized proteins on microtitration plates in ELISA: Application for detection of autoantibodies in Myasthenia gravis. Journal of Biotechnology, 72, 115-125 (1999). 14. K.V. NGUYEN, C.M. WOLFF, D. MEYER, P. POINDRON and J.M. WARTER Utilization of nucleotide probes for the measurement of specific messenger RNA: Application for molecular diagnosis of autosomal recessive spinal muscular atrophy. Analytical Letters, 35, 1135-1148 (2002). 15. K.V. NGUYEN, J.L. GENDRAULT and C.M. WOLFF Poly-L-lysine dissolves fibrillar aggregation of the Alzheimer ?-amyloid peptide in vitro. Biochemical and Biophysical Research Communications, 291, 764-768 (2002). 16. C.M. WOLFF, K.V. NGUYEN and P. REMY Cloning and expression of the Surfeit locus member Surf-6 during embryogenesis in Xenopus laevis. DNA Sequence, 13, 149-152 (2002). The nucleotide sequence reported in this paper has been deposited in the GenBank data base under the accession number AJ276843.1. 17. R.K. NAVIAUX and K.V. NGUYEN POLG mutations associated with Alpers syndrome and mitochondrial DNA depletion. Annals of Neurology, 55, 706-712 (2004). 18. K.V. NGUYEN RT-PCR-based cloning of the human beta-amyloid precursor protein gene and the construction of its expression plasmids. Analytical Letters, 38, 71-88 (2005). Curriculum Vitae Khue Nguyen 16 19. K.V. NGUYEN RT-PCR-based cloning of human SMN, the SMA determining gene, and the construction of its expression plasmids. Analytical Letters, 38, 1351-1365 (2005). 20. R.K. NAVIAUX and K.V. NGUYEN POLG mutations associated with Alpers syndrome and mitochodrial DNA depletion. Annals of Neurology, 58, 491 (2005). 21. K.V. NGUYEN, E. OSTERGAARD, S.H. RAVN, T. BALSLEV, E.R. DANIELSEN, A. VARDAG, P.J. McKIERNAN, G. GRAY and R.K. NAVIAUX POLG mutations in Alpers syndrome. Neurology, 65, 1493-1495 (2005). 22. K.V. NGUYEN Selection of peptide ligands specific for baculovirus DNA-binding protein from the FliTrxTM random peptide display library. Analytical Letters, 39, 99-112 (2006). 23. K.V. NGUYEN, F. SHARIEF, S. S. L. CHAN, W.C. COPELAND and R.K. NAVIAUX Molecular diagnosis of Alpers syndrome. Journal of Hepatology, 45, 108-116 (2006). 24. K.V. NGUYEN Utilization of nucleotide probes in ELISA procedure for the quantitative determination of baculovirus titer. Analytical Letters, 40, 513-528 (2007). 25. K.V. NGUYEN Utilization of nucleotide probes in PCR-ELISA procedure for the quantitative determination of Plasmodium falciparum DNA in malaria. Analytical Letters, 40, 2045- 2065 (2007). 26. K.V. NGUYEN Human p53 and Hdm2: Cloning and construction of expression plasmid. Analytical Letters, 43, 323-334 (2010). Curriculum Vitae Khue Nguyen 17 27. K.V. NGUYEN, R.K. NAVIAUX, S. PATRA, B.A. BARSHOP and W.L. NYHAN Novel mutations in the human MCCA and MCCB gene causing methylcrotonylglycinuria. Molecular Genetics and Metabolism, 102, 218-221 (2011). 28. K.V. NGUYEN, R.K. NAVIAUX, K.K. PAIK and W.L. NYHAN Novel mutations in the human HPRT gene. Nucleosides, Nucleotides and Nucleic Acids, 30, 440-445 (2011). 29. K.V. NGUYEN, R.K. NAVIAUX, K.K. PAIK and W.L. NYHAN Lesch-Nyhan syndrome: mRNA expression of HPRT in patients with enzyme proven deficiency of HPRT and normal HPRT coding region of the DNA. Molecular Genetics and Metabolism, 106, 498-501 (2012). 30. K.V. NGUYEN, R.K. NAVIAUX, K.K. PAIK, T. NAKAYAMA and W.L. NYHAN Lesch-Nyhan variant syndrome: real-time RT-PCR for mRNA quantification in variable presentation in three affected family members. Nucleosides, Nucleotides and Nucleic Acids, 31, 616-629 (2012). 31. K.V. NGUYEN, R. NGUYEN and W.L. NYHAN The human folate receptor 1 gene: molecular diagnostic of folate deficiency. International Journal of Medicine and Molecular Medicine, 3(6):WMC003461 (2012). 32. K.V. NGUYEN Antithrombin Hanoi: Arg 393 to His missense point mutation in antithrombin gene and cancer. International Journal of Medicine and Molecular Medicine, 3(9):WMC003720 (2012). 33. K.V. NGUYEN and W.L. NYHAN Identification of novel mutations in the human HPRT gene. Nucleosides, Nucleotides and Nucleic Acids, 32, 155-160 (2013). Curriculum Vitae Khue Nguyen 18 34. R. FU, I.C. PICOT, R.J. TORRES, L.E. LAROVERE, Y. YAMADA, K.V. NGUYEN, M. HEGDE, J.E. VISSER, D.J. SCHRETLEN, W.L. NYHAN, J.G. PUIG, P.J. O’NEILL, H.A. JINNAH and for the Lesch-Nyhan Disease International Group. Genotype-phenotype correlations in neurogenetics: Lesch-Nyhan disease as a model disorder. Brain, 137, 1282-1303 (2014). 35. K.V. NGUYEN Epigenetic regulation in amyloid precursor protein and the Lesch-Nyhan syndrome. Biochemical and Biophysical Research Communications, 446, 1091-1095 (2014). 36. K.V. NGUYEN The human ?-amyloid precursor protein: biomolecular and epigenetic aspects. Biomolecular Concepts, 6, 11-32 (2015). 37. K.V. NGUYEN and W.L. NYHAN Lesch-Nyhan syndrome in a family with a deletion followed by an insertion within the HPRT1 gene. Nucleosides, Nucleotides and Nucleic Acids, 34, 442-447 (2015). 38. K.V. NGUYEN Epigenetic regulation in amyloid precursor protein with genomic rearrangements and the Lesch-Nyhan syndrome. Nucleosides, Nucleotides and Nucleic Acids, 34, 674-690 (2015). 39. K.V. NGUYEN and W.L. NYHAN Mutation in the human HPRT1 gene and the Lesch-Nyhan syndrome. Nucleosides, Nucleotides and Nucleic Acids, 35, 426-433 (2016). Curriculum Vitae Khue Nguyen 19 40. K.V. NGUYEN, R.K. NAVIAUX and W.L. NYHAN Human HPRT1 gene and the Lesch-Nyhan disease: substitution of alanine for glycine and inversely in the HGprt enzyme protein. Nucleosides, Nucleotides and Nucleic Acids, 36, 151-157 (2017). 41. K.V. NGUYEN and W.L. NYHAN Quantification of various APP-mRNA isoforms and epistasis in Lesch-Nyhan disease. Neuroscience Letters, 643, 52-58 (2017). 42. K.V. NGUYEN, K. LEYDIKER, R. WANG, J. ABDENUR and W.L. NYHAN A neurodevelopmental disorder with a nonsense mutation in the Ox-2 antigen domain of the amyloid precursor protein (APP) gene. Nucleosides, Nucleotides and Nucleic Acids, 36, 317-327 (2017). 43. K.V. NGUYEN, S. SILVA, M. TRONCOSO, R.K. NAVIAUX and W.L. NYHAN Lesch-Nyhan disease in two families from Chiloe Island with mutations in the HPRT1 gene. Nucleosides, Nucleotides and Nucleic Acids, 36, 452-462 (2017). 44. K.V. NGUYEN Epigenetics in rare diseases. Journal of Rare Disorders: Diagnosis & Therapy, 3:1 (2017). 45. K.V. NGUYEN, R.K. NAVIAUX and W.L. NYHAN Novel mutation in the human HPRT1 gene and the Lesch-Nyhan disease. Nucleosides, Nucleotides and Nucleic Acids (submitted). 46. K.V. NGUYEN Epigenetics in rare diseases and the target for epigenetic therapy. Biomolecular Concepts


Calixto Machado Curbelo , Senior Professor, Editor Profiles

Dr. Calixto Machado graduated as MD in 1976. He continued his medical training to become Specialist in Neurology and Clinical Neurophysiology, First Degree in 1980, and Second Degree in 1984. In 1994 he became PhD, and in 2002 he was the youngest Dr. in Sciences (PhD - Second Degree) in his country. Dr. Machado received clinical training in specialized neurology centers in Sweden, Denmark, Canada, Italy, Austria, and the US. During the last 30 years he has run many research protocols, such as: brain death, coma, persistent vegetative states and other disorders of consciousness, stroke, autism, etc. He has published more than 450 peer reviewed articles, book chapters, and 7 books. His Book “Brain Death: A Reappraisal” has been recognized with great enthusiasm among neurologist, neurosurgeons, intensivists, and physicians specialized in transplants.


Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.

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Virginia E. Koenig

Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.

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Delcio G Silva Junior

Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.

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Ziemlé Clément Méda

Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.

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Mina Sherif Soliman Georgy

We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.

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Layla Shojaie

The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.

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Sing-yung Wu

Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.

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Orlando Villarreal

Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.

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Katarzyna Byczkowska

Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.

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Anthony Kodzo-Grey Venyo

Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.

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Pedro Marques Gomes

Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.

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Bernard Terkimbi Utoo

This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.

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Prof Sherif W Mansour

Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.

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Hao Jiang

As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.

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Dr Shiming Tang

Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.

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Raed Mualem

International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.

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Andreas Filippaios

Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.

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Dr Suramya Dhamija

Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.

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Bruno Chauffert

I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!

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Baheci Selen

"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

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Jesus Simal-Gandara

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

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Douglas Miyazaki

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

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Dr Griffith

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

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Dr Tong Ming Liu

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

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Husain Taha Radhi

I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

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S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

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Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

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George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

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Rui Tao